For safe and comfortable use of tampons, read and keep the leaflet that is found inside every tampon pack. When using tampons, always use the lowest absorbency for your flow and change your tampon every four to eight hours. Tampons are associated with Toxic Shock Syndrome (TSS). This is a rare but serious illness that may be fatal. More information on the risks and symptoms of TSS can be found in the leaflet provided inside tampon packs.